 Short Course 2 |
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| TOPIC |
| • BioMEMS and Lab-On-a-Chip Emerging Nanotechnologies for Health |
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| ORGANIZER AND PRESENTERS |
• Prof. Albert van den Berg, Mesa Institute, Twente University, The Netherlands (organizer)
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Prof. Helene Andersson, KTH, Stockholm, Sweden |
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| DURATION: 4 lectures of 1:30 hr |
| 08:00-09:00 |
Registration |
| 09:00-10:30 |
Classification of Lab on a Chip
Pr. Albert van den Berg |
| 10:30-11:00 |
Coffee break |
| 11:00-12:30 |
Microfluidics for DNA and protein analysis
Pr. Helene Andersson |
| 12:30-14:00 |
Lunch break |
| 14:00-15:30 |
Microfluidic devices for cell analysis
Pr. Helene Andersson |
| 15:30-16:00 |
Coffee break |
| 16:00-17:30 |
Nanofluidics and biomedical LOC examples
Pr. Albert van den Berg |
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| SUMMARY |
The course addresses engineers and researchers from companies or institutes active in analytical chemistry, manufacturing of analytical and medical instruments, pharmaceutical sector and bio sciences or in the manufacturing processes of micro devices. Target group is engineers, biochemists and analytical chemists that want an entry or update in the field of microfluidics. |
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| OUTLINE |
- Introduction to fluid mechanics - modeling/simulation - scaling laws
- Introduction in microtechnology for fabrication of microfluidic devices: silicon/glass/polymer techologies, patterning/etching/bonding/deposition techniques
- Mechanical microfluidic components: valves - pumps - flow sensors - mixers/filters - channels - nozzles
- Non-mechanical microfluidics: EOF - MHD - EHD - dielectrophoresis - acoustic actuation - T-sensor- hydrophobic patches - capillary based devices
- Labs-on-Chip (LOC) / Micro Total Analysis Systems
- Arrays vs. flow systems (microfluidics) - surface vs. beads based systems
- MS-interfacing: MALDI-TOF/ESI
- Applications: Biomedical devices and systems, diagnostics
- Genomics/proteomics/cell-based systems/tissue engineering
- Nanotechnology/nanofluidics/single molecule analysis
- Commercialization aspects
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| Biography of Presenters: |
Albert van den Berg received his PhD at the University of Twente in 1988 on the topic of chemically modified ISFETs. From 1988-1993 he worked in Neuchatel, Switzerland, at the CSEM and the University (IMT) on miniaturized chemical sensors. From 1993 until 1999 he was research director Micro Total Analysis Systems (μTAS) at MESA, University of Twente, a topic that was extended to Miniaturized Chemical Systems (MiCS) in 1999. In 1998 he was appointed as part-time professor “Biochemical Analysis Systems”, and later in 2000 as full professor on Miniaturized Systems for (Bio)Chemical Analysis in the faculty of Electrical Engineering, embedded the MESA+ Institute for Nanotechnology. In 2002 he received the Simon Stevin Master award from the Dutch Technical Science foundation (STW). In 2003 he was appointed as captain of the Nanofluidics Flagship within the national nanotechnology program Nanoned. In 2005 he stayed for 6 months San Diego (USA) at the La Jolla Insitute for Allergy and Immunology (LIAI, group Green) during a sabbatical leave. His current research interests focus on microanalysis systems and nanosensors, nanofluidics and single cells on chips. |
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Dr. Andersson Svahn is Associate Professor at the Royal Institute of Technology in Sweden heading the Nanobiotechnology department and Professor in Applied BIOMEMS at MESA+ Research Institute in Holland. Dr. Andersson Svahn received her Ph. D. in Electrical Engineering at the Royal Institute in 2001 and holds a M. Sc. in Molecular Biotechnology. Her main research focus is micro- and nano-fluidic devices for cell and protein analysis. Dr. Andersson Svahn has published numerous journal articles in the Lab-on-a-chip field and in 2003 Dr. Andersson Svahn was selected as member of the ‘TR100: Innovators under 35 who will create the future’ at MIT in USA. In 2006 Dr Andersson Svahn was awarded a prestigious 5 year research fellowship from the Royal Swedish Academy of Sciences.
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